Marco Gastini was born in Turin, where he lived and worked. Gastini has exhibited in several exhibitions in Italy and participated to the Venice Bienniale in 1976 and 1982.
Several museums in Italy and abroad have dedicated major anthological shows to Gastini over the years. The first of these was the Städtische Galerie im Lenbachhaus in Munich in 1982, followed by the Galleria Civica in Modena (1983) and PAC in Milan (1984).
Gastini dies in Turin on 28 September 2018.